To enlist the help of GPT-3, the researchers made use of one of its less well-known capabilities. The researchers tested their approach on a collection of 237 audio recordings taken from healthy volunteers and Alzheimer’s patients, which were converted to text using a pre-trained speech recognition model. “If the subject has some kind of issue Alzheimer’s, and that’s already reflected in the language, the hope is that we can use machine learning to pick up these kinds of signals that allow us to do early diagnostics.” “These large language models like GPT-3 are so powerful they can pick up these kind of subtle differences,” says Liang. They discovered it could discriminate between transcripts of speech from Alzheimer’s patients and healthy volunteers well enough to predict the disease with 80 percent accuracy, which represents state-of-the-art performance. Normally this relies on purpose-built models, but Liang and his colleagues wanted to see if they could repurpose the technology behind ChatGPT, OpenAI’s large language model GPT-3, to spot the telltale signs of Alzheimer’s. “The hope is that we can use machine learning to pick up these kinds of signals that allow us to do early diagnostics.” -Hoalou Liang, Drexel University This has led to growing interest in using machine learning to spot early signs of the disease in the way people talk. One of the most common and noticeable symptoms of the disease is problems with language, such as grammatical mistakes, pausing, repetition, or forgetting the meaning of words, says Liang. Diagnosing the disease typically requires brain imaging or lengthy cognitive evaluations though, which can be both expensive and time consuming and therefore unsuitable for widespread screening, says Hualou Liang a professor of biomedical engineering at Drexel University, in Philadelphia.Ī promising avenue for early detection of Alzheimer’s is automated speech analysis. But it turns out that the underlying technology could also help spot the early signs of Alzheimer’s disease, potentially making it possible to diagnose the debilitating condition sooner.Ĭatching Alzheimer’s early can significantly improve treatment options and give patients time to make lifestyle changes that could slow progression. The AI-powered chatbot ChatGPT is taking the Internet by a storm with its impressive language capabilities, helping to draw up legal contracts as well as write fiction.
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